Isaiah McGuire
Position: DL
Jersey #: 57
Date of Birth: July 27, 2001
Height / Weight: 6'4" / 266 lbs
College: Missouri
Drafted: Round , Pick 126 in 2023 by CLE
First Team: CLE (2023)
Last Team: CLE (2026)
Career Summary
Missouri defensive end
Isaiah McGuire played defensive end at Missouri. He came to the Tigers from Tulsa, Oklahoma.
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College Career
Leading Missouri's pass rush
McGuire led Missouri with six sacks in 2021 and again with 7.5 sacks in 2022. He totaled 27 tackles for loss across those two seasons and earned second-team All-SEC honors in 2022.
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Path to the NFL
Fourth-round selection
The Cleveland Browns selected McGuire in the fourth round of the 2023 NFL Draft with the 126th overall pick.
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Sources for this section
29588, 00-0038574, 2001-07-27, Isaiah McGuire, Isaiah, McGuire
MFT PLAYER RANKINGS
Current player ranking
#65Defensive Line
MFT Score: 79.8
2026 preseason baseline. Position-relative and updated through the site’s weekly review process.